Analisis Senyawa Paracetamol (Acetaminophen) dalam Sampel Urin Menggunakan Metode Kromatografi dan Spektrometri

Authors

  • Dianti Pratiwi Universitas Singaperbangsa Karawang (UNSIKA) Jawa Barat, Indonesia
  • Dila Qhoirul Nisa Universitas Singaperbangsa Karawang (UNSIKA) Jawa Barat, Indonesia
  • Elsya Martia Universitas Singaperbangsa Karawang (UNSIKA) Jawa Barat, Indonesia
  • Ivan Iduljana Universitas Singaperbangsa Karawang (UNSIKA) Jawa Barat, Indonesia
  • Nurma Dwi Rahmawati Universitas Singaperbangsa Karawang (UNSIKA) Jawa Barat, Indonesia
  • Sridevi Anggraini Universitas Singaperbangsa Karawang (UNSIKA) Jawa Barat, Indonesia

DOI:

https://doi.org/10.46799/jhs.v3i4.473

Keywords:

Paracetamol;, Acetaminophen, Gas Chrotography-Mass Spectrometry (CG-MS);, LC-MS (Liquid Chromathography – Mass Spectrometry);

Abstract

Paracetamol (acetaminophen) is a drug that has an analgesic-antipyretic effect. Research has been carried out with the aim of analyzing the compound paracetamol (acetaminophen) in urine qualitatively using Gas Chrotography-Mass Spectrometry (CG-MS) and LC-MS (Liquid Chromathography – Mass Spectrometry). Urine samples were obtained from patients taking paracetamol without changing consumption patterns. The results of the research analysis showed that positive results of acetaminophen-TMS were obtained in urine samples from 1 hour to a day after taking paracetamol tablets but negative results were obtained after more than 1 day of taking tablets.

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Published

2022-04-28