The Relationship Between Glycemic Control And Lipid Profile In Patients With Type 2 Diabetes Mellitus In Bangli Hospital
DOI:
https://doi.org/10.46799/jhs.v5i8.1346Keywords:
Diabetes Mellitus, Cholesterol, K-HDL, K-LDL, TriglyceridesAbstract
Diabetes Mellitus (DM) type 2 is susceptible to diabetic dyslipidemia, which is one of the factors in increasing the risk of complications from cardiovascular disease. The aim of this study was to determine the relationship between glycemic control and lipid profile in type 2 DM patients. A cross-sectional study was conducted at the Internal Medicine Polyclinic at Bangli Regional Hospital for the period January 2023-December 2023 and a total of 60 type 2 DM patients met the inclusion criteria. Patients were grouped into type 2 DM patients with controlled glycemic control (HbA1c < 7%) and uncontrolled (HbA1c?7%). Lower levels of total cholesterol (160,444 30,608 mg/dl vs 203,476 45,471 mg/dl; p= 0.001), triglycerides (125,500 56,019 vs 202,047 91,568; p= 0.002), low-density lipoprotein (K-LDL ) (93,072 28,443 vs 131,571 44,590; p= 0.001) in type 2 DM patients with good glycemic control. High-density lipoprotein (K-HDL) levels (50,022 14,050 vs 41,152 12,619; p = 0.019) were higher in type 2 DM patients with good glycemic control. From statistical tests, a positive correlation was found between total cholesterol levels (r = 0.277; p = 0.032), triglycerides (r = 0.386; p = 0.002) and K-LDL (r = 0.357; p = 0.005) with HbA1c levels. There is a negative correlation between K-HDL (r=-0.366; p = 0.004) and HbA1c levels. The significant correlation between HbA1c and lipid profile shows the importance of glycemic control in type 2 DM patients. This can be explained in the pathogenesis of type 2 DM in the advanced phase. There is a positive correlation between glycemic control (HbA1c) and total cholesterol, triglycerides and K-LDL. There is a negative correlation between glycemic control (HbA1c) and K-HDL.
References
Committee, W. H. O. Guidelines Approved by the Guidelines Review. (2011). Use of glycated haemoglobin (HbA1c) in the diagnosis of diabetes mellitus: abbreviated report of a WHO consultation. Geneva: World Health Organization.
Devhy, Ni Luh Putu, & Widana, Anak Agung GedeOka. (2019). Analisis Kelengkapan Rekam Medis Rawat Inap Rumah Sakit Ganesha Di Kota Gianyar tahun 2019 Completeness Analysis of Inpatien Ganesha Hospital Medical Records in Gianyar City in 2019. Jurnal Rekam Medis Dan Informasi Kesehatan, 2(2).
Goyal, Rajeev, Singhal, Mayank, & Jialal, Ishwarlal. (2023). Type 2 diabetes. StatPearls [Internet].
Handayani, U. F., Sofyan, A., Lestari, D., Sholikin, M. M., Wulandari, W., Harahap, M. A., Herdian, H., Julendra, H., Okselni, T., & Mahata, M. E. (2023). Dietary supplementation with tomato waste to improve performance and egg quality of laying hens: a meta-analysis. Journal of Animal & Feed Sciences, 32(3).
Indonesia, Perkumpulan Endokrinologi. (2021). Pedoman pengelolaan dan pencegahan Diabetes melitus Tipe 2 Dewasa di Indonesia. PB Perkeni, 46.
Kostapanos, Michael S., & Elisaf, Moses S. (2014). High density lipoproteins and type 2 diabetes: Emerging concepts in their relationship. World Journal of Experimental Medicine, 4(1), 1.
Kumar, Sushil, Kumari, Bandana, Kaushik, Amit, Banerjee, Ayan, Mahto, Mala, & Bansal, Akash. (2022). Relation between HbA1c and lipid profile among prediabetics, diabetics, and non-diabetics: A hospital-based cross-sectional analysis. Cureus, 14(12).
Nnakenyi, Ifeyinwa Dorothy, Nnakenyi, Emeka Francis, Parker, Elijah Joshua, Uchendu, Nene Orizu, Anaduaka, Emeka Godwin, & Ezeanyika, Lawrence Uchenna. (2022). Relationship between glycaemic control and lipid profile in type 2 diabetes mellitus patients in a low-resource setting. Pan African Medical Journal, 41(1).
Salsabila, Zhafirah, & Sjaaf, Amal C. (2022). The analysis of diabetes self-management implementation on type 2 diabetes mellitus patients: a protocol for systematic review and meta-analysis. Jurnal Ekonomi Kesehatan Indonesia, 7(2), 5.
Sulolipu, Andi Baji, Handoyo, Susilo, & Roziqin. (2019). Perlindungan Hukum Terhadap Profesi Dokter Dalam Penyelesaian Sengketa Medis Berdasarkan Prinsip Keadilan. Projudice.
Published
Issue
Section
License
Copyright (c) 2024 Made A.A. Pradnyani, I Ketut Sutarjana
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under aCreative Commons Attribution-ShareAlike 4.0 International (CC-BY-SA).�that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.